Affinity DataKd: 0.0530nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 0.0530nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 8.30nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m...More data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 126nMAssay Description:Binding affinity to GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 148nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged GSK3B (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged GSK3B (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataKd: 720nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 730nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 730nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 730nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 810nMAssay Description:Binding affinity to full-length human wild-type GSK-3-beta expressed in mammalian expression system assessed as dissociation constant by DiscoverX KI...More data for this Ligand-Target Pair
Affinity DataKd: 950nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 950nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 950nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair