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Found 14 Enz. Inhib. hit(s) with all data for entry = 50012360
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14457((+)-4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117937((+)4-(2-{4-[9-bromo-4-chloro-1-methyl-(12R)-3,6,7,...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117932((+/-)4-{2-[4-(9-bromo-4-chloro-1-methyl-3,6,7,12-t...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117931((-)4-(2-{4-[4-chloro-1-methyl-(12R)-3,6,7,12-tetra...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117931((-)4-(2-{4-[4-chloro-1-methyl-(12R)-3,6,7,12-tetra...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117933((+)1-[4-(10-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117939((+)1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,...)
Affinity DataIC50:  34nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117935((+)4-{2-[4-(4-chloro-3,6,7,12-tetrahydropyrido[2',...)
Affinity DataIC50:  42nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117936((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...)
Affinity DataIC50:  65nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117938((+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrah...)
Affinity DataIC50:  69nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117938((+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrah...)
Affinity DataIC50: >180nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117934((+ )1-[4-(4-chloro-1,3-dimethyl-3,6,7,12-tetrahydr...)
Affinity DataIC50: >190nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117936((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...)
Affinity DataIC50: >190nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed