Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50531422
Substrate
n/a
Meas. Tech.
ChEMBL_1920187 (CHEMBL4423032)
IC50
>6700±n/a nM
Citation
 Härter, M; Kalthof, B; Delbeck, M; Lustig, K; Gerisch, M; Schulz, S; Kast, R; Meibom, D; Lindner, N Novel non-xanthine antagonist of the A Eur J Med Chem 163:763-778 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2
Type:
PROTEIN
Mol. Mass.:
36460.91
Organism:
Mus musculus
Description:
ChEMBL_1515686
Residue:
319
Sequence:
MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADIAVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVFFSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRAVRLCQTSDSLDSNMEQTTE
  
Inhibitor
Name:
BDBM50531422
Synonyms:
CHEMBL4522981
Type:
Small organic molecule
Emp. Form.:
C18H22F3N3O4S
Mol. Mass.:
433.445
SMILES:
CCn1c(=O)n(CCC(F)(F)F)c2sc(C(=O)N3CCC(O)CC3)c(C)c2c1=O
Structure:
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