Compile Data Set for Download or QSAR
maximum 50k data
Found 1948 with Last Name = 'lustig' and Initial = 'k'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223890((S)-3-[3'-(2-cyclopropylamino-3,4-dioxo-cyclobut-1...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223891((S)-3-[3'-(2-cyclopropylamino-3,4-dioxo-cyclobut-1...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223897((S)-3-{3'-[(1H-imidazole-2-carbonyl)-amino]-biphen...)
Affinity DataKi:  1nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223888((S)-3-[3'-(4,5-dihydro-1H-imidazol-2-ylamino)-biph...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  2nMAssay Description:Inhibition of human A2B adenosine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM415448(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoimida...)
Affinity DataKi:  2.40nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50125289((S)-3-[3'-(3-Cyclopropyl-ureido)-biphenyl-4-yl]-2-...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM415450(3-Isopropyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoi...)
Affinity DataKi:  2.70nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM415451(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxo-2,3-...)
Affinity DataKi:  2.80nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM415449(3-Ethyl-5-methyl-1-(oxetan-2-ylmethyl)-6-[(2-oxoim...)
Affinity DataKi:  5.20nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM415452(3-Ethyl-5-methyl-6-[(5-oxo-4,5-dihydro-1H-1,2,4-tr...)
Affinity DataKi:  6.40nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223896((S)-3-[3'-(2-cyclopropylamino-3,4-dioxo-cyclobut-1...)
Affinity DataKi:  10nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223887((S)-3-(3'-{3,4-dioxo-2-[(pyridin-2-ylmethyl)-amino...)
Affinity DataKi:  11nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50125297((S)-3-(3'-Guanidino-biphenyl-4-yl)-2-(2,4,6-trimet...)
Affinity DataKi:  11nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM415453(3-Ethyl-5-methyl-6-[(5-oxo-1,5-dihydro-4H-1,2,4-tr...)
Affinity DataKi:  12nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223886((S)-3-[3'-(4-cyclopropylamino-1-oxo-1H-1lambda*4*-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336977(CHEMBL1672627 | N-[5-(3-Fluoropyridin-4-yl)-6-pyri...)
Affinity DataKi:  24nMAssay Description:Inhibition of human A2B adenosine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223892((S)-3-[3'-(2-benzylamino-3,4-dioxo-cyclobut-1-enyl...)
Affinity DataKi:  25nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223893((S)-3-{3'-[(1H-pyrrole-2-carbonyl)-amino]-biphenyl...)
Affinity DataKi:  33nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223891((S)-3-[3'-(2-cyclopropylamino-3,4-dioxo-cyclobut-1...)
Affinity DataKi:  47nMAssay Description:Binding affinity to GP2b3a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415451(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxo-2,3-...)
Affinity DataKi:  100nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415448(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoimida...)
Affinity DataKi:  120nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50125289((S)-3-[3'-(3-Cyclopropyl-ureido)-biphenyl-4-yl]-2-...)
Affinity DataKi:  128nMAssay Description:Binding affinity to GP2b3a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(3-Isopropyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoi...)
Affinity DataKi:  270nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(3-Ethyl-5-methyl-1-(oxetan-2-ylmethyl)-6-[(2-oxoim...)
Affinity DataKi:  280nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415448(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoimida...)
Affinity DataKi:  330nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(3-Ethyl-5-methyl-6-[(5-oxo-1,5-dihydro-4H-1,2,4-tr...)
Affinity DataKi:  330nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223895((S)-3-{3'-[(pyridine-3-carbonyl)-amino]-biphenyl-4...)
Affinity DataKi:  400nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415451(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxo-2,3-...)
Affinity DataKi:  590nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223885((S)-3-{3'-[(furan-2-carbonyl)-amino]-biphenyl-4-yl...)
Affinity DataKi:  650nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223889((S)-3-{3'-[(pyridine-4-carbonyl)-amino]-biphenyl-4...)
Affinity DataKi:  700nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(3-Ethyl-5-methyl-6-[(5-oxo-1,5-dihydro-4H-1,2,4-tr...)
Affinity DataKi:  790nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(3-Ethyl-5-methyl-1-(oxetan-2-ylmethyl)-6-[(2-oxoim...)
Affinity DataKi:  950nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM50531422(CHEMBL4522981)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human A1 adenosine receptor expressed in CHO cell membranes after 60 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM50531422(CHEMBL4522981)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CGS21680 from human A2A adenosine receptor expressed in HEK293 cell membranes after 120 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(3-Isopropyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoi...)
Affinity DataKi:  1.10E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415452(3-Ethyl-5-methyl-6-[(5-oxo-4,5-dihydro-1H-1,2,4-tr...)
Affinity DataKi:  1.50E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415452(3-Ethyl-5-methyl-6-[(5-oxo-4,5-dihydro-1H-1,2,4-tr...)
Affinity DataKi:  1.70E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50223894((S)-3-{3'-[(pyridine-2-carbonyl)-amino]-biphenyl-4...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to integrin alphavbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(3-Ethyl-5-methyl-6-[(5-oxo-1,5-dihydro-4H-1,2,4-tr...)
Affinity DataKi:  3.30E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(3-Ethyl-5-methyl-1-(oxetan-2-ylmethyl)-6-[(2-oxoim...)
Affinity DataKi:  6.80E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM50531422(CHEMBL4522981)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in HEK293 cell membranes after 120 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10849(1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human A2B adenosine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415448(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoimida...)
Affinity DataKi:  1.10E+4nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415451(3-Ethyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxo-2,3-...)
Affinity DataKi:  1.40E+4nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(3-Isopropyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoi...)
Affinity DataKi:  1.60E+5nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM302404(US9598416, Example 50)
Affinity DataIC50:  0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM194899(US9206184, 80)
Affinity DataIC50:  0.200nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM302362(6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...)
Affinity DataIC50:  0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataIC50:  0.200nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...More data for this Ligand-Target Pair
In DepthDetails US Patent
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