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TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2nMAssay Description:In vitro for anti-HDAC1 (Histone deacetylase 1) activity in mouse A20 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50221738(CHEMBL1790595)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97708(US8476255, 96)
Affinity DataIC50:  10nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97707(US8476255, 95)
Affinity DataIC50:  10nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97695(US8476255, 55)
Affinity DataIC50:  20nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50366962(CHEMBL1790586)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97698(US8476255, 59)
Affinity DataIC50:  30nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97703(US8476255, 89)
Affinity DataIC50:  30nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50366966(CHEMBL1790596)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50195609(CHEMBL216147 | N-hydroxy-4-(3,4-dihydro-6-phenyl-4...)
Affinity DataIC50:  34nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97685(US8476255, 28)
Affinity DataIC50:  36nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50002746(CHEMBL217545)
Affinity DataIC50:  36.7nMAssay Description:Inhibition of mouse HDAC1 (mean)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234054(6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  39nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234054(6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  39nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97706(US8476255, 94)
Affinity DataIC50:  40nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97704(US8476255, 90)
Affinity DataIC50:  40nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97697(US8476255, 58)
Affinity DataIC50:  40nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97694(US8476255, 53)
Affinity DataIC50:  40nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234055(CHEMBL217494 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  40nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234055(CHEMBL217494 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  40nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97680(US8476255, 19)
Affinity DataIC50:  42nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97684(US8476255, 27)
Affinity DataIC50:  50nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97700(US8476255, 77)
Affinity DataIC50:  50nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50002747(CHEMBL217546)
Affinity DataIC50:  50.9nMAssay Description:Inhibition of mouse HDAC1 (mean)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97688(US8476255, 32)
Affinity DataIC50:  52nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97687(US8476255, 31)
Affinity DataIC50:  54nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97686(US8476255, 29)
Affinity DataIC50:  57nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50195605(CHEMBL214533 | N-hydroxy-3-(3,4-dihydro-6-phenyl-4...)
Affinity DataIC50:  57nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97699(BOC-LYS(AC)-AMC | US8476255, 76)
Affinity DataIC50:  60nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97693(US8476255, 52)
Affinity DataIC50:  60nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97701(US8476255, 84)
Affinity DataIC50:  60nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97683(US8476255, 24)
Affinity DataIC50:  62nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50366961(CHEMBL1790599)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity against histone deacetylases (HDAC1) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97709(US8476255, 101)
Affinity DataIC50:  70nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM97696(US8476255, 57)
Affinity DataIC50:  70nMT: 37°CAssay Description:Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...More data for this Ligand-Target Pair
In DepthDetails US Patent


LigandPNGBDBM50366962(CHEMBL1790586)
Affinity DataIC50:  84nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50195615(CHEMBL218348 | N-hydroxy-3-(3,4-dihydro-6-benzyl-4...)
Affinity DataIC50:  90nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration gainst Histone deacetylase 1 derived from NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234114(6-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  103nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234114(6-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  103nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50195600(CHEMBL216850 | N-hydroxy-4-(3,4-dihydro-6-benzyl-4...)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  112nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  112nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  112nMAssay Description:Inhibition of mouse liver HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 1(Mouse)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  112nMAssay Description:In vitro for anti-HDAC1 (Histone deacetylase 1) activity in mouse A20 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

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