54 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents.
University of Kentucky
Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant
University of Kentucky
1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.
University of Kentucky
Muscarinic acetylcholine receptor binding affinities of pethidine analogs.
University of Kentucky
Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
University of Kentucky
2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2.
University of Kentucky
Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.
University of Kentucky
Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake.
University of Kentucky
Saquayamycins G-K, cytotoxic angucyclines from Streptomyces sp. Including two analogues bearing the aminosugar rednose.
University of Kentucky
Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.
University of Kentucky
Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2).
University of Kentucky
Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding.
University of Kentucky
Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners.
University of Kentucky
Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.
University of Kentucky
Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate.
University of Kentucky
SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase.
University of Kentucky
Phosphoramidate peptide inhibitors of human skin fibroblast collagenase.
University of Kentucky
Prostaglandin photoaffinity probes: synthesis and biological activity of azide-substituted 16-phenoxy- and 17-phenyl-PGF2 alpha prostaglandins.
University of Kentucky
bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors.
University of Kentucky
Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues.
University of Kentucky
VX-322: a novel dual receptor tyrosine kinase inhibitor for the treatment of acute myelogenous leukemia.
University of Kentucky
Novel human mPGES-1 inhibitors identified through structure-based virtual screening.
University of Kentucky
Discovery of non-peptide, small molecule antagonists ofa9a10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.
University of Kentucky
Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release.
University of Kentucky
Quinlobelane: a water-soluble lobelane analogue and inhibitor of VMAT2.
University of Kentucky
Regiospecific and conformationally restrained analogs of melphalan and DL-2-NAM-7 and their affinities for the large neutral amino acid transporter (system LAT1) of the blood-brain barrier.
University of Kentucky
QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum.
University of Kentucky
Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release.
University of Kentucky
Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2.
University of Kentucky
Searching for Synthetic Opioid Rescue Agents: Identification of a Potent Opioid Agonist with Reduced Respiratory Depression.
University of Kentucky
Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity.
University of Kentucky
Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.
University of Kentucky
Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands.
University of Kentucky
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from
University of Kentucky
Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.
University of Kentucky
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M.
University of Kentucky
Macrocyclic Immunoproteasome Inhibitors as a Potential Therapy for Alzheimer's Disease.
University of Kentucky
Structural Revision of Garcinielliptin Oxide and Garcinielliptone E.
University of Kentucky
LMP2 Inhibitors as a Potential Treatment for Alzheimer's Disease.
University of Kentucky
Synthesis and in vitro evaluation of water-soluble 1,4-diphenethylpiperazine analogs as novel inhibitors of the vesicular monoamine transporter-2.
University of Kentucky
N,N'-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents.
University of Kentucky
Discovery of potent and selective butyrylcholinesterase inhibitors through the use of pharmacophore-based screening.
University of Kentucky
Development of Novel Epoxyketone-Based Proteasome Inhibitors as a Strategy To Overcome Cancer Resistance to Carfilzomib and Bortezomib.
University of Kentucky
Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M
University of Kentucky
Improving the inhibitory activity of arylidenaminoguanidine compounds at the N-methyl-D-aspartate receptor complex from a recursive computational-experimental structure-activity relationship study.
University of Kentucky
Design, synthesis, and discovery of 5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones and related derivatives as novel inhibitors of mPGES-1.
University of Kentucky
Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [
University of Kentucky
Selective inhibitors of human mPGES-1 from structure-based computational screening.
University of Kentucky
C-aryl glucoside derivative, preparation methods thereof, and medical applications thereof
Youngene Therapeutics