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28 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
15
Synthesis, characterization, hypoglycemic and aldose reductase inhibition activity of arylsulfonylspiro[fluorene-9,5'-imidazolidine]-2',4'-diones.EBI
Quaid-I-Azam University
16
Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents.EBI
University of Messina
4
Nicotinamide adenine dinucleotide phosphate-decanaldehyde adduct as an inhibitor of beef brain NADP-linked aldehyde reductase.EBI
TBA
20
Synthesis of organic nitrates of luteolin as a novel class of potent aldose reductase inhibitors.EBI
Xiangtan University
13
Identification of new non-carboxylic acid containing inhibitors of aldose reductase.EBI
University of Messina
9
Synthesis, induced-fit docking investigations, and in vitro aldose reductase inhibitory activity of non-carboxylic acid containing 2,4-thiazolidinedione derivatives.EBI
University of Messina
7
Evaluation of in vitro aldose redutase inhibitory activity of 5-arylidene-2,4-thiazolidinediones.EBI
University of Messina
16
Discovery of novel aldose reductase inhibitors using a protein structure-based approach: 3D-database search followed by design and synthesis.EBI
Sankyo
23
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors.EBI
Modena and Reggio Emilia
20
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors.EBI
TBA
26
Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1.EBI
Wyeth-Ayerst Research
126
Spiro hydantoin aldose reductase inhibitors.EBI
Pfizer
14
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications.EBI
University of Messina
23
In vitro evaluation of 5-arylidene-2-thioxo-4-thiazolidinones active as aldose reductase inhibitors.EBI
University of Messina
11
Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin.EBI
Central South University
2
 
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductaseEBI
TBA
28
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors.EBI
Dipartimento Di Scienze Farmaceutiche
15
Synthesis, activity, and molecular modeling of new 2, 4-dioxo-5-(naphthylmethylene)-3-thiazolidineacetic acids and 2-thioxo analogues as potent aldose reductase inhibitors.EBI
Ep811-Cnrs
1
N-substituted spirosuccinimide, spiropyridazine, spiroazetidine, and acetic acid aldose reductase inhibitors derived from isoquinoline-1,3-diones. 2.EBI
Wyeth-Ayerst Research
11
Spiro oxazolidinedione aldose reductase inhibitors.EBI
TBA
3
N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.EBI
TBA
1
Synthesis, absolute configuration, and conformation of the aldose reductase inhibitor sorbinil.EBI
TBA
3
Computer-assisted design and synthesis of novel aldose reductase inhibitors.EBI
Wyeth-Ayerst Research
1
(Pyrimidinyloxy)acetic acids and pyrimidineacetic acids as a novel class of aldose reductase inhibitors.EBI
Wyeth-Ayerst Research
4
Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.EBI
Wyeth-Ayerst Research
1
Quinazolineacetic acids and related analogues as aldose reductase inhibitors.EBI
Wyeth-Ayerst Research