BDB TargetNames

Target Names are taken from UniProtKB. To view the associated UniProt page, click on the UniProt ID. When we have data for a given Target in multiple species or for mutants of a given Target, we provide a header row (upper case, bold font) with all of the data followed by a separate for each species or variant of the Target.

Target Name

Organism

Affinity Links

Articles

UniProts

Files

H(+)-exporting diphosphatase Q8MTZ4

Trypanosoma brucei

IC50: 81

Pasteurella multocida

Kd: 3

Histone deacetylase 2b Q94F81

Maize

IC50: 233

HDAC5 PROTEIN A0A7G2HKG3 A0A7G2HKP9 B1WBY8 O15379 P56524 Q13547 Q4QQW4 Q5RJZ2 Q6P6W3 Q7K6A1 Q8WUI4 Q92769 Q969S8 Q96DB2 Q99P96 Q99P97 Q99P99 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9ZTP8

Ki: 23 IC50: 2174 EC50: 94

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

p53 binding protein Q9H4C2

Human

IC50: 6

Heat sensitive channel TRPV3 Q4QYD9

Rat

IC50: 21 EC50: 17

HEAT SHOCK 70 KDA PROTEIN 1A P0DMV8 V9GZ37

Human

Ki: 14 IC50: 116 Kd: 12

Heat shock 70 kDa protein 1A V9GZ37

Human

IC50: 97

Heat shock 70 kDa protein 1A P0DMV8

Human

Ki: 14 IC50: 19 Kd: 12

HEAT SHOCK COGNATE 71 KDA PROTEIN P11142 P19120

IC50: 63 Kd: 63

Heat shock cognate 71 kDa protein P11142

Human

IC50: 63 Kd: 62

Heat shock cognate 71 kDa protein P19120

Bovine

Kd: 1

HEAT SHOCK FACTOR PROTEIN 1 P38532 Q00613

IC50: 421 EC50: 4374

Heat shock factor protein 1 P38532

Mouse

EC50: 4317

Heat shock factor protein 1 Q00613

Human

IC50: 421 EC50: 57

Endoplasmin/Heat shock protein 75/Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta A9CPF9 P07900 P08238 P14625

American alligator

IC50: 137

Heat shock protein 75 kDa, mitochondrial Q12931

Human

Ki: 47 IC50: 114 Kd: 4

Heat shock protein 90 homolog P46598

Yeast

EC50: 53

Heat shock protein 90, putative Q8IL32

Plasmodium falciparum (isolate 3D7)

Kd: 5

Heat shock protein beta-1 P04792

Human

IC50: 7 Kd: 10

HEAT SHOCK PROTEIN FAMILY A (HSP70) MEMBER 1A P0DMV8 V9GZ37

Human

Ki: 14 IC50: 116 Kd: 12

Heat shock 70 kDa protein 1A V9GZ37

Human

IC50: 97

Heat shock 70 kDa protein 1A P0DMV8

Human

Ki: 14 IC50: 19 Kd: 12

Heat shock protein HSP 90 P11500

Rabbit

IC50: 16

HEAT SHOCK PROTEIN HSP 90-ALPHA A9CPF9 P07900 P07901 P08238 P14625 Q76LV2

Ki: 168 IC50: 3281 Kd: 556 EC50: 214 Koff: 7

Endoplasmin/Heat shock protein 75/Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta A9CPF9 P07900 P08238 P14625

American alligator

IC50: 137

Heat shock protein HSP 90-alpha Q76LV2

Bovine

IC50: 29

Heat shock protein HSP 90-alpha P07900

Human

Ki: 159 IC50: 2305 Kd: 409 EC50: 89 Koff: 7

Heat shock protein HSP 90-alpha P07901

Mouse

EC50: 54

Heat shock protein HSP 90-alpha [1-236] P07900

Human

Kd: 7

Heat shock protein HSP 90-alpha/90-beta P07900 P08238

Human

Ki: 9 IC50: 810 Kd: 140 EC50: 71

HEAT SHOCK PROTEIN HSP 90-BETA A9CPF9 P07900 P08238 P14625

Ki: 136 IC50: 1869 Kd: 326 EC50: 248

Endoplasmin/Heat shock protein 75/Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta A9CPF9 P07900 P08238 P14625

American alligator

IC50: 137

Heat shock protein HSP 90-alpha/90-beta P07900 P08238

Human

Ki: 9 IC50: 810 Kd: 140 EC50: 71

Heat shock protein HSP 90-beta P08238

Human

Ki: 127 IC50: 922 Kd: 186 EC50: 177

Heat shock protein hsp-16.2 P06582

Caenorhabditis elegans

IC50: 127

Heat shock-related 70 kDa protein 2 P54652

Human

Ki: 54 IC50: 4

HEMAGGLUTININ B4URE7 C3W5S1 C5MVR7 K7N5L2 P03437 P03438 P03452 P12590 Q20N24 Q20N27 Q6DM53 Q9QMU3

Ki: 2 IC50: 52 Kd: 25 EC50: 30

Hemagglutinin C3W5S1

Influenza A virus (strain swl A/California/04/2009 H1N1)

IC50: 16

Hemagglutinin Q9QMU3

Influenza B virus (B/Victoria/70)

IC50: 10

Hemagglutinin Q6DM53

Influenza A virus (A/Shangdong/9/93(H3N2))

Ki: 2 IC50: 2

Hemagglutinin C5MVR7

Influenza A virus (A/reassortant/NIBRG-121(California/07/2009 x PR8)(H1N1))

EC50: 4

Hemagglutinin P12590

Influenza A virus (strain A/Taiwan/1/1986 H1N1)

IC50: 9

Hemagglutinin K7N5L2

Influenza A virus

IC50: 1

Hemagglutinin B4URE7

Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1))

Kd: 9

Hemagglutinin P03438

Influenza A virus (strain A/X-31 H3N2)

IC50: 2 EC50: 5

Hemagglutinin P03452

Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)

IC50: 4 Kd: 16

Hemagglutinin P03437

Influenza A virus (strain A/Aichi/2/1968 H3N2)

IC50: 8

Hemagglutinin/Neuraminidase Q20N24 Q20N27

Influenza A virus (A/Weiss/1943(H1N1))

EC50: 21

Hemagglutinin-neuraminidase Q06992

Human parainfluenza virus 1

IC50: 12

HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE O35543 O60760 Q9JHF7

Ki: 30 IC50: 469 Kd: 35 EC50: 68

Hematopoietic prostaglandin D synthase O60760

Human

Ki: 27 IC50: 455 Kd: 35 EC50: 5

Hematopoietic prostaglandin D synthase Q9JHF7

Mouse

Ki: 3

Hematopoietic prostaglandin D synthase O35543

Rat

IC50: 14 EC50: 63

Heme ligase Q8IL04

Plasmodium falciparum (isolate 3D7)

Ki: 8 IC50: 12 Kd: 1

Iron-starvation protein PigA O69002

Pseudomonas aeruginosa

Kd: 59

HEME OXYGENASE 1 P06762 P09601

IC50: 345 EC50: 126

Heme oxygenase 1 P06762

Rat

IC50: 339

Heme oxygenase 1 P09601

Human

IC50: 6 EC50: 126

HEME OXYGENASE 2 P23711 P30519

IC50: 294

Heme oxygenase 2 P23711

Rat

IC50: 289

Heme oxygenase 2 P30519

Human

IC50: 5

HEME OXYGENASE HUTZ Q9KL41

Vibrio cholerae

Kd: 5

Heme oxygenase HutZ [D132E] Q9KL41

Vibrio cholerae

Kd: 2

Heme oxygenase HutZ [D132L] Q9KL41

Vibrio cholerae

Kd: 1

Heme oxygenase HutZ [D132N] Q9KL41

Vibrio cholerae

Kd: 2

HEME-BINDING PROTEIN A A3N3U8 B8F653

Kd: 6

Heme-binding protein A A3N3U8

Actinobacillus pleuropneumoniae

Kd: 3

Heme-binding protein A B8F653

Haemophilus parasuis

Kd: 3

Heme-binding protein HutZ C3LWH1

Vibrio cholerae

Kd: 2

Hemoglobin HbA P68871 P69905

Human

IC50: 1

HEMOGLOBIN SUBUNIT BETA P68871 P69905

Human

IC50: 9

Hemoglobin HbA P68871 P69905

Human

IC50: 1

Hemoglobin subunit beta P68871

Human

IC50: 8

HEPARANASE Q6YGZ1 Q9Y251

Ki: 25 IC50: 466 Kd: 34

Heparanase Q9Y251

Human

Ki: 24 IC50: 465 Kd: 34

Heparanase Q6YGZ1

Mouse

Ki: 1 IC50: 1

HEPATIC SODIUM/BILE ACID COTRANSPORTER P26435 Q14973

Ki: 8 IC50: 83 Kd: 1 EC50: 276

Sodium/bile acid cotransporter P26435

Rat

IC50: 3

Sodium/bile acid cotransporter Q14973

Human

Ki: 8 IC50: 80 Kd: 1 EC50: 276

Hepatic triacylglycerol lipase P11150

Human

IC50: 418

Hepatitis A virus cellular receptor 2 Q8TDQ0

Human

Ki: 21 IC50: 2 Kd: 24

Hepatocyte growth factor P14210

Human

Kd: 1

Hepatocyte growth factor activator Q04756

Human

Ki: 79 IC50: 30 EC50: 3

HEPATOCYTE GROWTH FACTOR RECEPTOR F6ZDS4 P00533 P07949 P08581 P16056 Q75ZY9 Q9UM73

Ki: 397 IC50: 7848 Kd: 319 EC50: 86

ALK tyrosine kinase/Hepatocyte growth factor receptor P08581 Q9UM73

Human

IC50: 3

Epidermal/Hepatocyte growth factor receptor P00533 P08581

Human

IC50: 3

Hepatocyte growth factor receptor P08581

Human

Ki: 391 IC50: 6435 Kd: 319 EC50: 86

Hepatocyte growth factor receptor P16056

Mouse

Ki: 1 IC50: 5

Hepatocyte growth factor receptor Q75ZY9

Dog

IC50: 4

Hepatocyte growth factor receptor MET Isoform 2 [974-1390,A1209G,V1290L] P08581

Human

IC50: 65

Hepatocyte growth factor receptor [1-13,15-1390] P08581

Human

IC50: 153

Hepatocyte growth factor receptor [1038-1346] P08581

Human

IC50: 51

Hepatocyte growth factor receptor [1078-1345,D1228H,L1272V] P08581

Human

Ki: 1

Hepatocyte growth factor receptor [1078-1345,H1094R,L1272V] P08581

Human

Ki: 1

Hepatocyte growth factor receptor [1078-1345,M1250T,L1272V] P08581

Human

Ki: 1

Hepatocyte growth factor receptor [1078-1345,V1092I,L1272V] P08581

Human

Ki: 1

Hepatocyte growth factor receptor [1078-1345,Y1230H,L1272V] P08581

Human

Ki: 1

Hepatocyte growth factor receptor [960-1390] P08581

Human

IC50: 6

Hepatocyte growth factor receptor [974-1390,A1209G,V1290L] P08581

Human

IC50: 42

Hepatocyte growth factor receptor [D1228H] P08581

Human

IC50: 153

Hepatocyte growth factor receptor [D1228N] P08581

Human

IC50: 153

Hepatocyte growth factor receptor [F1200I] P08581

Human

IC50: 151

Hepatocyte growth factor receptor [L1195V] P08581

Human

IC50: 149

Hepatocyte growth factor receptor [Y1230C] P08581

Human

IC50: 153

Hepatocyte growth factor receptor [Y1230H] P08581

Human

IC50: 153

Hepatocyte growth factor receptor [Y1230S] P08581

Human

IC50: 152

Hepatocyte growth factor receptor/Nucleoprotein TPR F6ZDS4 P16056

Mouse

IC50: 1

Hepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret P07949 P08581

Human

IC50: 3

Isoform 2 of Hepatocyte growth factor receptor (2) P08581

Human

IC50: 13

Hepatocyte growth factor-like protein P26927

Human

IC50: 5

Hepatocyte nuclear factor 4-alpha P41235

Human

IC50: 234 EC50: 8

Hepcidin P81172

Human

IC50: 4

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 P09651

Human

Kd: 3

Heterogeneous nuclear ribonucleoprotein A1 P09651

Human

Kd: 1

Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) P09651

Human

Kd: 1

Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) 68-320] P09651

Human

Kd: 1

Hexokinase HKDC1 [W721R] Q2TB90

Human

IC50: 433 EC50: 104

HEXOKINASE-1 P04806 P19367

IC50: 32 EC50: 101

Hexokinase-1 P04806

Baker's yeast

IC50: 7

Hexokinase-1 P19367

Human

IC50: 25 EC50: 101

HEXOKINASE-2 P27881 P52789

Ki: 2 IC50: 54 Kd: 1

Hexokinase-2 P27881

Rat

Ki: 1

Hexokinase-2 P52789

Human

Ki: 1 IC50: 54 Kd: 1

HEXOKINASE-4 P17712 P35557 P52792

IC50: 99 Kd: 12 EC50: 1488

Hexokinase-4 P35557

Human

IC50: 98 Kd: 12 EC50: 1292

Hexokinase-4 P52792

Mouse

EC50: 76

Hexokinase-4 P17712

Rat

IC50: 1 EC50: 66

Hexokinase-4 P35557

Human

EC50: 54

Hexosaminidase D Q8WVB3

Human

IC50: 1

Putative sugar transporter O97467

malaria parasite P. falciparum

Ki: 32 IC50: 59

HIGH AFFINITY 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7A P70453 Q13946 Q9NP56

Ki: 30 IC50: 850

High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Q13946

Human

Ki: 28 IC50: 804

High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A P70453

Mouse

IC50: 1

High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B Q13946 Q9NP56

Human

Ki: 2 IC50: 45

HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A O60658 O95263

Human

Ki: 12 IC50: 158

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A O60658

Human

Ki: 12 IC50: 157

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A/8B O60658 O95263

Human

IC50: 1

HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A O70628 O76083 Q8QZV1

Ki: 273 IC50: 1063 EC50: 3

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083

Human

Ki: 138 IC50: 916

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Q8QZV1

Rat

IC50: 100

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O70628

Mouse

IC50: 2 EC50: 3

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [226-593] O76083

Human

IC50: 10

Isoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2) O76083

Human

Ki: 135 IC50: 35

HIGH AFFINITY CHOLINE TRANSPORTER 1 Q8BGY9 Q9GZV3 Q9JMD7

Ki: 42 IC50: 63 EC50: 60

High affinity choline transporter 1 Q8BGY9

Mouse

Ki: 38 IC50: 7

High affinity choline transporter 1 Q9GZV3

Human

Ki: 3 IC50: 55 EC50: 60

High affinity choline transporter 1 Q9JMD7

Rat

Ki: 1 IC50: 1

High affinity immunoglobulin epsilon receptor subunit alpha P12319

Human

IC50: 7

High affinity immunoglobulin gamma Fc receptor I P12314

Human

IC50: 13

HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR P04629 P35739

Ki: 15 IC50: 9241 Kd: 216 EC50: 43

High affinity nerve growth factor receptor P04629

Human

Ki: 15 IC50: 8201 Kd: 216 EC50: 42

High affinity nerve growth factor receptor P35739

Rat

IC50: 6 EC50: 1

High affinity nerve growth factor receptor [440-796] P04629

Human

IC50: 4

High affinity nerve growth factor receptor [441-796] P04629

Human

IC50: 905

High affinity nerve growth factor receptor [G595R] P04629

Human

IC50: 19

High affinity nerve growth factor receptor [G667C] P04629

Human

IC50: 64

Isoform TrkA-I of High affinity nerve growth factor receptor (TrkAI) P04629

Human

IC50: 42

High mobility group protein B1 P09429

Human

Kd: 25

HISTAMINE H1 RECEPTOR A5D795 P30546 P31389 P31390 P35367 P70174

Ki: 2499 IC50: 657 Kd: 207 EC50: 102

Histamine H1 receptor P35367

Human

Ki: 1946 IC50: 411 Kd: 139 EC50: 48

Histamine H1 receptor P31389

Guinea pig

Ki: 264 IC50: 195 Kd: 68 EC50: 54

Histamine H1 receptor P70174

Mouse

Ki: 2

Histamine H1 receptor A5D795

Bovine

Ki: 2

Histamine H1 receptor P30546

Bovine

Ki: 1

Histamine H1 receptor P31390

Rat

Ki: 284 IC50: 51

HISTAMINE H2 RECEPTOR G1TWL8 L8IRW0 P25021 P25102 P47747 P97292

Ki: 729 IC50: 142 Kd: 106 EC50: 403

Histamine H2 receptor P47747

Guinea pig

Ki: 94 IC50: 26 Kd: 32 EC50: 153

Histamine H2 receptor P25021

Human

Ki: 626 IC50: 93 Kd: 71 EC50: 228

Histamine H2 receptor P97292

Mouse

Ki: 1

Histamine H2 receptor L8IRW0

wild yak

Ki: 1

Histamine H2 receptor G1TWL8

Rabbit

Ki: 2

Histamine H2 receptor P25102

Rat

Ki: 5 IC50: 23 Kd: 3 EC50: 22

HISTAMINE H3 RECEPTOR G7N499 P58406 Q9JI35 Q9QYN8 Q9Y5N1

Ki: 7003 IC50: 962 Kd: 134 EC50: 435

Histamine H3 receptor Q9Y5N1

Human

Ki: 4507 IC50: 921 Kd: 65 EC50: 408

Histamine H3 receptor Q9QYN8

Rat

Ki: 2012 IC50: 14 Kd: 13 EC50: 22

Histamine H3 receptor G7N499

Rhesus macaque

Ki: 69

Histamine H3 receptor Q9JI35

Guinea pig

Ki: 331 IC50: 13 Kd: 54 EC50: 1

Histamine H3 receptor P58406

Mouse

Ki: 84 IC50: 14 Kd: 2 EC50: 4

HISTAMINE H4 RECEPTOR E1BBS2 Q91ZY1 Q91ZY2 Q91ZY3 Q9H3N8

Ki: 2061 IC50: 212 Kd: 88 EC50: 407 Other: 1

Histamine H4 receptor Q9H3N8

Human

Ki: 1963 IC50: 208 Kd: 70 EC50: 330 Other: 1

Histamine H4 receptor Q91ZY2

Mouse

Ki: 33 IC50: 4 Kd: 13 EC50: 48

Histamine H4 receptor Q91ZY1

Rat

Ki: 51 Kd: 5 EC50: 29

Histamine receptor H4 E1BBS2

Bovine

Ki: 1

Histamine receptor H4 Q91ZY3

Guinea pig

Ki: 13

HISTAMINE N-METHYLTRANSFERASE P50135 Q01984 Q9EST2

Ki: 7 IC50: 36

Histamine N-methyltransferase P50135

Human

Ki: 5

Histamine N-methyltransferase Q01984

Rat

IC50: 36

Histamine N-methyltransferase Q9EST2

Guinea pig

Ki: 2

Histamine oxidase Q59118

Arthrobacter globiformis

IC50: 3

HISTAMINE RECEPTOR H3 F1MML8 Q865E1 Q865E3

Ki: 137

Histamine receptor H3 Q865E1

Rhesus macaque

Ki: 127

Histamine receptor H3 F1MML8

Bovine

Ki: 1

Histamine receptor H3 Q865E3

Dog

Ki: 9

HISTAMINE RECEPTOR H4 E1BBS2 Q91ZY3

Ki: 14

Histamine receptor H4 E1BBS2

Bovine

Ki: 1

Histamine receptor H4 Q91ZY3

Guinea pig

Ki: 13

Histidine biosynthesis bifunctional protein HisB P06987

Escherichia coli (strain K12)

IC50: 10

Histidine decarboxylase P16453

Rat

Ki: 1

HISTIDINE KINASE A0A0H2UQD0 O32393 Q9X688

Ki: 1 IC50: 20

Adenylate cyclase O32393

Spirulina platensis

IC50: 6

Histidine kinase Q9X688

Caulobacter vibrioides

Ki: 1 IC50: 12

Histidine kinase A0A0H2UQD0

Streptococcus pneumoniae PCS8203

IC50: 2

Histidine kinase 3 Q9C5U1

Mouse-ear cress

EC50: 16

Histidine kinase 4 Q9C5U0

Mouse-ear cress

EC50: 11

Histidine protein kinase SaeS Q2G2U1

Staphylococcus aureus (strain NCTC 8325 / PS 47)

IC50: 2 Kd: 2

Histidine--tRNA ligase, cytoplasmic P12081

Human

IC50: 1

Histidine-binding periplasmic protein [1-238] P0AEU0

Escherichia coli (Enterobacteria)

Kd: 1 ITC: 1

Histidine-rich protein PFHRP-II P05227

malaria parasite P. falciparum

IC50: 164

Histidinol dehydrogenase Q8G2R2

Brucella suis

IC50: 30

Histidinol dehydrogenase, chloroplastic P24226

Cabbage

Ki: 4 IC50: 12

Histo-blood group ABO system transferase P16442

Human

Ki: 7 IC50: 2 Kd: 3

HISTONE ACETYLTRANSFERASE GCN5 Q03330 Q245K9

IC50: 252 Kd: 2

Histone acetyltransferase Q245K9

Tetrahymena thermophila (strain SB210)

IC50: 3

Histone acetyltransferase GCN5 Q03330

Baker's yeast

IC50: 249 Kd: 2

Histone acetyltransferase KAT2A Q92830

Human

Ki: 2 IC50: 23 Kd: 19

HISTONE ACETYLTRANSFERASE KAT2B Q92831

Human

Ki: 3 IC50: 406 Kd: 66

Histone acetyltransferase KAT2B Q92831

Human

Ki: 3 IC50: 292 Kd: 66

Histone acetyltransferase KAT2B [719-832] Q92831

Human

IC50: 114

Histone acetyltransferase KAT5 Isoform 2 [2-461] Q92993

Human

Ki: 55 IC50: 592

HISTONE ACETYLTRANSFERASE KAT6A Q8BZ21 Q92794

Ki: 202 IC50: 1455

Histone acetyltransferase KAT6A Q8BZ21

Mouse

IC50: 1

Histone acetyltransferase KAT6A [507-778] Q92794

Human

Ki: 202 IC50: 1454

Histone acetyltransferase KAT6B [431-2073] Q8WYB5

Human

Ki: 78 IC50: 65

Histone acetyltransferase KAT7 [325-611] O95251

Human

Ki: 128 IC50: 545

Histone acetyltransferase KAT8 [177-447] Q9H7Z6

Human

Ki: 62 IC50: 497 Kd: 3

HISTONE ACETYLTRANSFERASE P300 O14929 Q09472 Q14814 Q16665 Q92793

Human

Ki: 12 IC50: 1433 Kd: 67 EC50: 46

CREB-binding protein/Histone acetyltransferase p300 Q09472 Q92793

Human

IC50: 110 Kd: 15 EC50: 46

Histone acetyltransferase p300 Q09472

Human

Ki: 11 IC50: 895 Kd: 52

Histone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit O14929 Q09472

Human

IC50: 391

Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha Q09472 Q16665

Human

Ki: 1 IC50: 15

Histone acetyltransferase p300/Myocyte-specific enhancer factor 2D Q09472 Q14814

Human

IC50: 22

HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT O14929 Q09472

Human

IC50: 393

Histone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit O14929 Q09472

Human

IC50: 391

Histone acetyltransferase type B catalytic subunit O14929

Human

IC50: 2

Histone chaperone ASF1A Q9Y294

Human

IC50: 36

HISTONE DEACETYLASE A0A7G2HKG3 A0A7G2HKP9 A5H660 B1WBY8 O15379 P56524 Q13547 Q4QQW4 Q5RJZ2 Q6P6W3 Q7K6A1 Q8VH37 Q8WUI4 Q92769 Q969S8 Q96DB2 Q99P96 Q99P97 Q99P99 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9ZTP8

Ki: 23 IC50: 2435 Kd: 3 EC50: 94

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

Histone deacetylase 8 Q8VH37

Mouse

IC50: 4

Histone deacetylase 8 A5H660

Blood fluke

IC50: 257 Kd: 3

HISTONE DEACETYLASE 1 A0A7G2HKG3 A0A7G2HKP9 B1WBY8 O09106 O15379 O88895 P56524 P70288 Q13547 Q4QQW4 Q5RJZ2 Q6NZM9 Q6P3E7 Q6P6W3 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q99P96 Q99P97 Q99P99 Q9BY41 Q9P2K3 Q9UBN7 Q9UKV0 Q9UQL6 Q9Y618 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 185 IC50: 13549 Kd: 129 EC50: 218 Other: 20 ITC: 2

H1/H5-depleted chromatin P56524 Q13547

Human

ITC: 2

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase (HDAC1 and HDAC2) Q13547 Q92769

Human

IC50: 467

Histone deacetylase 1 Q13547

Human

Ki: 159 IC50: 10555 Kd: 129 EC50: 49 Other: 20

Histone deacetylase 1 O09106

Mouse

IC50: 77

Histone deacetylase 1 Q4QQW4

Rat

IC50: 19

Histone deacetylase 1/11/4/6/8 P56524 Q13547 Q96DB2 Q9BY41 Q9UBN7

Human

IC50: 49

Histone deacetylase 1/2/3 O15379 Q13547 Q92769

Human

IC50: 3 EC50: 1

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/2/3/6 O15379 Q13547 Q92769 Q9UBN7

Human

IC50: 68

Histone deacetylase 1/2/3/8 O15379 Q13547 Q92769 Q9BY41

Human

IC50: 110 EC50: 74

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

Histone deacetylase 1/Nuclear receptor corepressor 2 [395-498] Q13547 Q9Y618

Human

IC50: 17

Histone deacetylase 1/REST corepressor 3 Q13547 Q9P2K3

Human

Ki: 3

HISTONE DEACETYLASE 11 A0A7G2HKG3 A0A7G2HKP9 O09106 O15379 O88895 P56524 P70288 Q13547 Q5RJZ2 Q6NZM9 Q6P3E7 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 64 IC50: 3440 EC50: 94

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/11/4/6/8 P56524 Q13547 Q96DB2 Q9BY41 Q9UBN7

Human

IC50: 49

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 11 Q96DB2

Human

Ki: 41 IC50: 1208

HISTONE DEACETYLASE 2 A0A7G2HKG3 A0A7G2HKP9 O09106 O15379 O88895 P56524 P70288 Q13547 Q5RJZ2 Q6NZM9 Q6P3E7 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Y618 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 145 IC50: 6642 Kd: 104 EC50: 170

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase (HDAC1 and HDAC2) Q13547 Q92769

Human

IC50: 467

Histone deacetylase 1/2/3 O15379 Q13547 Q92769

Human

IC50: 3 EC50: 1

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/2/3/6 O15379 Q13547 Q92769 Q9UBN7

Human

IC50: 68

Histone deacetylase 1/2/3/8 O15379 Q13547 Q92769 Q9BY41

Human

IC50: 110 EC50: 74

Histone deacetylase 2 Q92769

Human

Ki: 122 IC50: 3794 Kd: 104 EC50: 1

Histone deacetylase 2/Nuclear receptor corepressor 2 [395-498] Q92769 Q9Y618

Human

IC50: 17

HISTONE DEACETYLASE 3 A0A7G2HKG3 A0A7G2HKP9 B1WBY8 O09106 O15379 O75376 O88895 P56524 P70288 Q13547 Q4QQW4 Q5RJZ2 Q6NZM9 Q6P3E7 Q6P6W3 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q99P96 Q99P97 Q99P99 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Y618 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 103 IC50: 6532 Kd: 2 EC50: 170 Other: 21

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/2/3 O15379 Q13547 Q92769

Human

IC50: 3 EC50: 1

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/2/3/6 O15379 Q13547 Q92769 Q9UBN7

Human

IC50: 68

Histone deacetylase 1/2/3/8 O15379 Q13547 Q92769 Q9BY41

Human

IC50: 110 EC50: 74

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

Histone deacetylase 3 O15379

Human

Ki: 61 IC50: 3606 Kd: 1 EC50: 1 Other: 21

Histone deacetylase 3/Nuclear receptor corepressor 1 O15379 O75376

Human

IC50: 2

Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) O15379 Q9Y618

Human

Ki: 19 IC50: 538 Kd: 1

Histone deacetylase 3/Nuclear receptor corepressor 2 [395-489] O15379 Q9Y618

Human

IC50: 4

Histone deacetylase 3/Nuclear receptor corepressor 2 [395-498] O15379 Q9Y618

Human

IC50: 17

HISTONE DEACETYLASE 4 A0A7G2HKG3 A0A7G2HKP9 B1WBY8 O09106 O15379 O88895 P56524 P70288 Q13547 Q14814 Q4QQW4 Q5RJZ2 Q6NZM9 Q6P3E7 Q6P6W3 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q99P96 Q99P97 Q99P99 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 136 IC50: 4208 Kd: 6 EC50: 114 Other: 33 ITC: 2

H1/H5-depleted chromatin P56524 Q13547

Human

ITC: 2

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/11/4/6/8 P56524 Q13547 Q96DB2 Q9BY41 Q9UBN7

Human

IC50: 49

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

Histone deacetylase 4 P56524

Human

Ki: 113 IC50: 1721 Kd: 6 EC50: 20 Other: 17

Histone deacetylase 4 [2-1084] P56524

Human

IC50: 46

Histone deacetylase 4 [627-1085] P56524

Human

IC50: 4

Histone deacetylase 4 [648-1032] P56524

Human

IC50: 24

Histone deacetylase 4 [648-729,745-1057] P56524

Human

IC50: 16

Histone deacetylase 4 [653-1084,H976Y] P56524

Human

IC50: 32 Other: 16

Histone deacetylase 4/Myocyte-specific enhancer factor 2D P56524 Q14814

Human

IC50: 132

HISTONE DEACETYLASE 5 A0A7G2HKG3 A0A7G2HKP9 O09106 O15379 O88895 P56524 P70288 Q13547 Q5RJZ2 Q6NZM9 Q6P3E7 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 102 IC50: 3038 EC50: 94 Other: 1

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 5 Q9UQL6

Human

Ki: 79 IC50: 850 Other: 1

Histone deacetylase 5 Q9Z2V6

Mouse

IC50: 5

HISTONE DEACETYLASE 6 A0A7G2HKG3 A0A7G2HKP9 B1WBY8 F8W4B7 O09106 O15379 O88895 P56524 P70288 Q13547 Q4QQW4 Q5RJZ2 Q6NZM9 Q6P3E7 Q6P6W3 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q99P96 Q99P97 Q99P99 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 180 IC50: 11070 Kd: 93 EC50: 178 Other: 11

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/11/4/6/8 P56524 Q13547 Q96DB2 Q9BY41 Q9UBN7

Human

IC50: 49

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/2/3/6 O15379 Q13547 Q92769 Q9UBN7

Human

IC50: 68

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

Histone deacetylase 6 Q9UBN7

Human

Ki: 147 IC50: 8629 Kd: 86 EC50: 81 Other: 11

Histone deacetylase 6 F8W4B7

Zebrafish

IC50: 4

Histone deacetylase 6 Q9Z2V5

Mouse

IC50: 124 EC50: 3

Histone deacetylase 6 [25-831] F8W4B7

Zebrafish

IC50: 2

Histone deacetylase 6 [440-798,S531A] F8W4B7

Zebrafish

Kd: 1

Histone deacetylase 6 [440-798] F8W4B7

Zebrafish

Ki: 8 IC50: 8 Kd: 1

Histone deacetylase 6 [60-420,H82F,F202Y] F8W4B7

Zebrafish

Kd: 1

Histone deacetylase 6 [60-420] F8W4B7

Zebrafish

Ki: 1 IC50: 1 Kd: 1

Histone deacetylase 6 [84-835,H255V] Q9UBN7

Human

Kd: 1

Histone deacetylase 6 [84-835,H651V] Q9UBN7

Human

Kd: 1

Histone deacetylase 6 [84-835] Q9UBN7

Human

Ki: 1 IC50: 1 Kd: 1

HISTONE DEACETYLASE 7 A0A7G2HKG3 A0A7G2HKP9 B1WBY8 O09106 O15379 O88895 P56524 P70288 Q13547 Q4QQW4 Q5RJZ2 Q6NZM9 Q6P3E7 Q6P6W3 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q99P96 Q99P97 Q99P99 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 62 IC50: 2900 Kd: 22 EC50: 95

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/3/4/6/7 B1WBY8 Q4QQW4 Q5RJZ2 Q6P6W3 Q99P96 Q99P97 Q99P99

Rat

IC50: 1

Histone deacetylase 7 Q8WUI4

Human

Ki: 39 IC50: 711 Kd: 22 EC50: 1

Histone deacetylase 7 [518-592] Q8WUI4

Human

IC50: 4

Isoform 5 of Histone deacetylase 7 (5) 18-991] Q8WUI4

Human

IC50: 1

HISTONE DEACETYLASE 8 A0A7G2HKG3 A0A7G2HKP9 A5H660 O09106 O15379 O88895 P56524 P70288 Q13547 Q5RJZ2 Q6NZM9 Q6P3E7 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 160 IC50: 6676 Kd: 53 EC50: 172 Other: 1 ITC: 8

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/11/4/6/8 P56524 Q13547 Q96DB2 Q9BY41 Q9UBN7

Human

IC50: 49

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 1/2/3/8 O15379 Q13547 Q92769 Q9BY41

Human

IC50: 110 EC50: 74

Histone deacetylase 8 Q8VH37

Mouse

IC50: 4

Histone deacetylase 8 A5H660

Blood fluke

IC50: 257 Kd: 3

Histone deacetylase 8 (HDAC8) Q9BY41

Human

Ki: 137 IC50: 4072 Kd: 50 EC50: 4 Other: 1 ITC: 8

Histone deacetylase 8 [R223M] Q9BY41

Human

IC50: 1

HISTONE DEACETYLASE 9 A0A7G2HKG3 A0A7G2HKP9 O09106 O15379 O88895 P56524 P70288 Q13547 Q5RJZ2 Q6NZM9 Q6P3E7 Q7K6A1 Q8C2B3 Q8VH37 Q8WUI4 Q91WA3 Q92769 Q969S8 Q96DB2 Q99N13 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6 Q9Z2V5 Q9Z2V6 Q9ZTP8

Ki: 57 IC50: 2939 EC50: 95

Histone deacetylase Q7K6A1

Plasmodium falciparum (isolate 3D7)

IC50: 37

Histone deacetylase A0A7G2HKG3

Cryptosporidium parvum

IC50: 30

Histone deacetylase A0A7G2HKP9

Cryptosporidium parvum

Ki: 11 IC50: 18

Histone deacetylase Q9ZTP8

Maize

IC50: 71

Histone deacetylase Q5RJZ2

Rat

IC50: 50

Histone deacetylase O15379 P56524 Q13547 Q8WUI4 Q92769 Q969S8 Q96DB2 Q9BY41 Q9UBN7 Q9UKV0 Q9UQL6

Human

Ki: 12 IC50: 1967 EC50: 94

Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 O09106 O88895 P70288 Q6NZM9 Q6P3E7 Q8C2B3 Q8VH37 Q91WA3 Q99N13 Q9Z2V5 Q9Z2V6

Mouse

IC50: 10

Histone deacetylase 9 Q9UKV0

Human

Ki: 34 IC50: 752 EC50: 1

Histone deacetylase 9 [604-1066] Q9UKV0

Human

IC50: 4

Histone deacetylase-like amidohydrolase Q70I53

Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188))

Ki: 11 IC50: 11 Kd: 22

HISTONE DEMETHYLASE UTY O14607

Human

Kd: 3

Histone demethylase UTY [818-1347,P1214I] O14607

Human

Kd: 1

Histone demethylase UTY [818-1347,S1138G] O14607

Human

Kd: 1

Histone demethylase UTY [818-1347] O14607

Human

Kd: 1

Histone H1.0 P07305

Human

Ki: 7

HISTONE H3.1 P68431

Human

IC50: 6 EC50: 3

Histone H3.1 P68431

Human

EC50: 3

Histone H3.1 [22-45] P68431

Human

IC50: 3

Histone H3.1 [22-45] P68431

Human

IC50: 3

HISTONE H4 O60885 P62805

Human

IC50: 78 Kd: 1

Bromodomain-containing protein 4 [44-168]/Histone H4 O60885 P62805

Human

IC50: 61

Bromodomain-containing protein 4/Histone H4 O60885 P62805

Human

IC50: 17

Histone H4 P62805

Human

Kd: 1

HISTONE LYSINE DEMETHYLASE PHF8 Q9UPP1

Human

IC50: 167

Histone lysine demethylase PHF8 Q9UPP1

Human

IC50: 112

Isoform 2 of Histone lysine demethylase PHF8 (2) Q9UPP1

Human

IC50: 55

HISTONE-ARGININE METHYLTRANSFERASE CARM1 Q86X55 Q9WVG6

Ki: 15 IC50: 2436 Kd: 12

Histone-arginine methyltransferase CARM1 Q9WVG6

Mouse

IC50: 51

Histone-arginine methyltransferase CARM1 Q86X55

Human

Ki: 15 IC50: 2385 Kd: 12

HISTONE-BINDING PROTEIN RBBP4 A0A090N8E9 O75530 Q09028 Q15022 Q15910 Q6ZN18 Q92800

Human

IC50: 1537

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH1/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q6ZN18 Q92800

Human

IC50: 26

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2 [Y641F]/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q15910 Q6ZN18

Human

IC50: 206

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12 O75530 Q09028 Q15022 Q15910

Human

IC50: 80

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q15910 Q6ZN18

Human

IC50: 981

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 A0A090N8E9 O75530 Q09028 Q15022 Q6ZN18

Human

IC50: 3

Histone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q6ZN18

Human

IC50: 241

HISTONE-LYSINE N-METHYLTRANSFERASE 2A O00255 P61964 Q03164 Q15291 Q969U6 Q9C005 Q9UBL3

Human

Ki: 263 IC50: 298 Kd: 15

Histone-lysine N-methyltransferase 2A Q03164

Human

Ki: 10 IC50: 36 Kd: 15

Histone-lysine N-methyltransferase 2A P61964 Q03164

Human

IC50: 89

Histone-lysine N-methyltransferase 2A/Menin O00255 Q03164

Human

Ki: 253 IC50: 31

Histone-lysine N-methyltransferase 2A/Retinoblastoma-binding protein 5/Set1/Ash2 histone methyltransferase complex subunit ASH2/WD repeat-containing protein 5 P61964 Q03164 Q15291 Q9UBL3

Human

IC50: 12

MLL1-WRAD2 complex Q03164 Q15291 Q969U6 Q9C005 Q9UBL3

Human

IC50: 58

P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] P61964 Q03164 Q15291 Q9C005 Q9UBL3

Human

IC50: 72

Histone-lysine N-methyltransferase 2B Q9UMN6

Human

IC50: 3

Histone-lysine N-methyltransferase 2C Q8NEZ4

Human

IC50: 1

Histone-lysine N-methyltransferase 2D O14686

Human

IC50: 2

Histone-lysine N-methyltransferase ASH1L Q9NR48

Human

IC50: 2

Histone-lysine N-methyltransferase E(z) P42124

Fruit fly

IC50: 2

Histone-lysine N-methyltransferase EHMT1 Q9H9B1

Human

IC50: 241 Kd: 12

HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2 Q96KQ7 Q9Z148

Ki: 40 IC50: 945 Kd: 17 EC50: 7

Histone-lysine N-methyltransferase EHMT2 Q96KQ7

Human

Ki: 40 IC50: 940 Kd: 16 EC50: 7

Histone-lysine N-methyltransferase EHMT2 Q9Z148

Mouse

IC50: 5 Kd: 1

HISTONE-LYSINE N-METHYLTRANSFERASE EZH1 O75530 Q09028 Q15022 Q6ZN18 Q92800

Human

Ki: 1 IC50: 122

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH1/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q6ZN18 Q92800

Human

IC50: 26

Histone-lysine N-methyltransferase EZH1 Q92800

Human

Ki: 1 IC50: 96

HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 A0A090N8E9 B5DFE2 O75530 Q09028 Q15022 Q15910 Q6ZN18

Ki: 212 IC50: 6461 Kd: 19 EC50: 84

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2 [Y641F]/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q15910 Q6ZN18

Human

IC50: 206

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12 O75530 Q09028 Q15022 Q15910

Human

IC50: 80

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 O75530 Q09028 Q15022 Q15910 Q6ZN18

Human

IC50: 981

Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 A0A090N8E9 O75530 Q09028 Q15022 Q6ZN18

Human

IC50: 3

Histone-lysine N-methyltransferase EZH2 Q15910

Human

Ki: 212 IC50: 2883 Kd: 18 EC50: 84

Histone-lysine N-methyltransferase EZH2 B5DFE2

Rat

IC50: 1

Histone-lysine N-methyltransferase EZH2 [2-746,Y641N] Q15910

Human

IC50: 204

Histone-lysine N-methyltransferase EZH2 [A677G] Q15910

Human

IC50: 64

Histone-lysine N-methyltransferase EZH2 [A677G] Q15910

Human

IC50: 62

Histone-lysine N-methyltransferase EZH2 [A687V] Q15910

Human

IC50: 62

Histone-lysine N-methyltransferase EZH2 [Y641F] Q15910

Human

IC50: 664

Histone-lysine N-methyltransferase EZH2 [Y641F]/Polycomb protein EED/Polycomb protein SUZ12 O75530 Q15022 Q15910

Human

IC50: 63

Histone-lysine N-methyltransferase EZH2 [Y641H] Q15910

Human

IC50: 2

Histone-lysine N-methyltransferase EZH2 [Y641N] Q15910

Human

IC50: 2

Histone-lysine N-methyltransferase EZH2 [Y641S] Q15910

Human

IC50: 2

Histone-lysine N-methyltransferase EZH2/Polycomb protein EED O75530 Q15910

Human

IC50: 105

Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12 [559-739] A0A090N8E9 O75530 Q15022

Human

Kd: 1

Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12 O75530 Q15022 Q15910

Human

IC50: 1077

Histone-lysine N-methyltransferase KMT5B Q4FZB7

Human

IC50: 5

Histone-lysine N-methyltransferase KMT5C Q86Y97

Human

IC50: 7

Histone-lysine N-methyltransferase NSD2 O96028

Human

IC50: 419 Kd: 21

Histone-lysine N-methyltransferase NSD3 Q9BZ95

Human

IC50: 4 Kd: 7

Histone-lysine N-methyltransferase PRDM9 [195-385] Q9NQV7

Human

Kd: 8

Histone-lysine N-methyltransferase PR-Set7 Q9VFK6

Fruit fly

IC50: 2

Histone-lysine N-methyltransferase SETD1B Q9UPS6

Human

IC50: 2

Histone-lysine N-methyltransferase SETD2 Q9BYW2

Human

IC50: 71 Kd: 1

Histone-lysine N-methyltransferase SETD7 Q8WTS6

Human

Ki: 2 IC50: 119 Kd: 2

Histone-lysine N-methyltransferase SETDB1 Q15047

Human

IC50: 6 Kd: 9

Histone-lysine N-methyltransferase SETMAR Q53H47

Human

IC50: 3

Histone-lysine N-methyltransferase SMYD3 Q9H7B4

Human

Ki: 11 IC50: 1822 EC50: 45

Histone-lysine N-methyltransferase Su(var)3-9 P45975

Fruit fly

IC50: 3

Histone-lysine N-methyltransferase SUV39H1 O43463

Human

Ki: 11 IC50: 14

Histone-lysine N-methyltransferase SUV39H2 Q9H5I1

Human

IC50: 316

Histone-lysine N-methyltransferase, H3 lysine-36 specific Q96L73

Human

IC50: 6 Kd: 1

HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC Q8TEK3

Human

Ki: 118 IC50: 230 Kd: 27 EC50: 4 Koff: 4 Kon: 4

Histone-lysine N-methyltransferase, H3 lysine-79 specific Q8TEK3

Human

Ki: 118 IC50: 221 Kd: 27 EC50: 4 Koff: 4 Kon: 4

Histone-lysine N-methyltransferase, H3 lysine-79 specific [1-416] Q8TEK3

Human

IC50: 9

Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5 Q8X225

Neurospora crassa

IC50: 1

HIV-1 PROTEASE O90781 O90783 O90785 Q9YQ34

Human immunodeficiency virus

Ki: 425 IC50: 58 EC50: 21

HIV-1 protease O90785

Human immunodeficiency virus

Ki: 43 IC50: 48 EC50: 10

HIV-1 protease Q9YQ34

Human immunodeficiency virus

Ki: 28 EC50: 11

HIV-1 protease O90783

Human immunodeficiency virus

Ki: 13

HIV-1 protease O90781

Human immunodeficiency virus

Ki: 341 IC50: 10

HLA class I histocompatibility antigen, A alpha chain P04439

Human

IC50: 152 Kd: 7

MHC class II antigen D7RIG0

Human

IC50: 105

HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN P04233 P08922

Human

IC50: 27

HLA class II histocompatibility antigen gamma chain P04233

Human

IC50: 25

HLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS P04233 P08922

Human

IC50: 2

HLA class II histocompatibility antigen, DR beta 3 chain P79483

Human

IC50: 27

Holo-[acyl-carrier-protein] synthase P96618

Bacillus subtilis (strain 168)

IC50: 22

Homeobox C9 F7C4A2

clawed frog

Ki: 4

Homeobox protein Nkx-2.5/Transcription factor GATA-4 P42582 Q08369

Mouse

IC50: 80

Homeobox protein PKNOX1 P55347

Human

IC50: 48

Homeobox-leucine zipper protein PROTODERMAL FACTOR 2 Q93V99

Mouse-ear cress

IC50: 2

Homeodomain-interacting protein kinase 1 Q86Z02

Human

Ki: 2 IC50: 63 Kd: 83

Homeodomain-interacting protein kinase 2 Q9H2X6

Human

Ki: 2 IC50: 88 Kd: 82

Homeodomain-interacting protein kinase 3 Q9H422

Human

IC50: 42 Kd: 82

Homeodomain-interacting protein kinase 4 Q8NE63

Human

IC50: 18 Kd: 84

Homoisocitrate dehydrogenase Q76G12

Deinococcus radiodurans

Ki: 5

Homoisocitrate dehydrogenase, mitochondrial P40495

Baker's yeast

Ki: 7

Homoserine kinase P00547

Escherichia coli (strain K12)

Ki: 6

Hormonally up-regulated neu tumor-associated kinase P57058

Human

Kd: 79

HORMONE-SENSITIVE LIPASE P15304 Q05469

Ki: 1 IC50: 592

Hormone-sensitive lipase Q05469

Human

IC50: 429

Hormone-sensitive lipase P15304

Rat

Ki: 1 IC50: 163

HPr kinase/phosphorylase O34483

Bacillus subtilis (strain 168)

IC50: 2 EC50: 7

Hrh3 protein Q5PPG3

Rat

Ki: 152

Hsp90 chaperone protein kinase-targeting subunit Q5KHW9

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 /ATCC MYA-565) (Filobasidiella neoformans)

EC50: 113

Hsp90 co-chaperone Cdc37 Q16543

Human

IC50: 30 EC50: 25

HTH-type quorum-sensing regulator RhlR P54292

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

IC50: 10 EC50: 3

HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR A0R666 P9WMC1

IC50: 17 Kd: 8 EC50: 47

HTH-type transcriptional regulator EthR P9WMC1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 16 Kd: 8 EC50: 47

HTH-type transcriptional regulator EthR A0R666

Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacteriumsmegmatis)

IC50: 1

HTH-type transcriptional regulator ExsA P26993

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

IC50: 21

HTH-type transcriptional regulator MgrA P0C1S0

Staphylococcus aureus

IC50: 8

HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR Q9AIU0

ITC: 23

Transcriptional Regulator TtgR Q9AIU0

Pseudomonas putida

ITC: 19

Transcriptional Regulator TtgR-DNA Q9AIU0

null

ITC: 4

Glyoxylate Regulatory Protein (C-AllR) P0ACN4

Escherichia coli (strain K12)

ITC: 1

Transducer protein HtrVI Q9HRA1

Halobacterium salinarum R1

Ki: 2

Huntingtin P42858

Human

IC50: 382 Kd: 2 EC50: 6

Hyaluronan mediated motility receptor O75330

Human

Kd: 12

Hyaluronate lyase Q54873

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

IC50: 1

HYALURONIDASE-1 Q12794 Q5E985 Q8SQG8

IC50: 23

Hyaluronidase-1 Q12794

Human

IC50: 22

Hyaluronidase-1/Hyaluronidase-2 Q5E985 Q8SQG8

Bovine

IC50: 1

Hyaluronidase-1/Hyaluronidase-2 Q5E985 Q8SQG8

Bovine

IC50: 1

Hydrolase, alpha/beta hydrolase fold family O69638

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

IC50: 1

Hydroxyacid oxidase 1 I3LVF1

Pig

IC50: 1

HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL O35952 Q16775 Q3B7M2

Ki: 12 IC50: 1

Hydroxyacylglutathione hydrolase, mitochondrial Q16775

Human

Ki: 4 IC50: 1

Hydroxyacylglutathione hydrolase, mitochondrial O35952

Rat

Ki: 5

Hydroxyacylglutathione hydrolase, mitochondrial Q3B7M2

Bovine

Ki: 3

HYDROXYCARBOXYLIC ACID RECEPTOR 1 B9UM26 G3V906 Q8C131 Q9BXC0

EC50: 62

Hydroxycarboxylic acid receptor 1 Q9BXC0

Human

EC50: 56

Hydroxycarboxylic acid receptor 1 B9UM26

Dog

EC50: 1

Hydroxycarboxylic acid receptor 1 Q8C131

Mouse

EC50: 1

RCG21202 G3V906

Rat

EC50: 4

HYDROXYCARBOXYLIC ACID RECEPTOR 2 Q80Z39 Q8TDS4 Q9EP66

Ki: 67 IC50: 375 EC50: 721

Hydroxycarboxylic acid receptor 2 Q8TDS4

Human

Ki: 47 IC50: 331 EC50: 685

Hydroxycarboxylic acid receptor 2 Q80Z39

Rat

Ki: 20 IC50: 4 EC50: 23

Hydroxycarboxylic acid receptor 2 Q9EP66

Mouse

IC50: 40 EC50: 13

Hydroxycarboxylic acid receptor 3 P49019

Human

IC50: 4 EC50: 86

Hydroxymethylglutaryl-CoA synthase, cytoplasmic P17425

Rat

IC50: 2

Hydroxyproline dehydrogenase [147-515] Q9UF12

Human

IC50: 14

HYDROXYSTEROID 11-BETA DEHYDROGENASE 1 Q56D22 Q5XX84

Ki: 1 IC50: 3

Hydroxysteroid 11-beta dehydrogenase 1 Q56D22

Rhesus macaque

IC50: 1

Hydroxysteroid 11-beta dehydrogenase 1 Q5XX84

Dog

Ki: 1 IC50: 2

Hypoxanthine phosphoribosyltransferase A0A0J9TE27

Plasmodium vivax

Ki: 23

HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE P00492 P9WHQ9 Q07010

Ki: 270 IC50: 2

Hypoxanthine-guanine phosphoribosyltransferase P00492

Human

Ki: 256 IC50: 2

Hypoxanthine-guanine phosphoribosyltransferase Q07010

Trypanosoma brucei brucei

Ki: 4

Hypoxanthine-guanine phosphoribosyltransferase P9WHQ9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 10

Hypoxanthine-guanine-xanthine phosphoribosyltransferase P20035

Plasmodium falciparum

Ki: 27

HYPOXIA-INDUCIBLE FACTOR 1-ALPHA P40337 Q09472 Q15369 Q15370 Q16665 Q61221 Q99814

Ki: 13 IC50: 1005 Kd: 2 EC50: 204

Elongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor P40337 Q15369 Q15370 Q16665

Human

IC50: 9

Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha Q16665 Q99814

Human

IC50: 422 EC50: 10

Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha Q09472 Q16665

Human

Ki: 1 IC50: 15

Hypoxia-inducible factor 1-alpha Q16665

Human

Ki: 12 IC50: 558 Kd: 2 EC50: 194

Hypoxia-inducible factor 1-alpha Q61221

Mouse

IC50: 1

Hypoxia-inducible factor 1-alpha inhibitor Q9NWT6

Human

Ki: 2 IC50: 70 Kd: 1

Curated by BindingDB

Curated by ChEMBL