BDBM50506263 CHEMBL4465054::US11401295, Compound 2',3'-cGAMP
SMILES [H][C@]12COP(O)(=O)O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(O)(=O)O[C@@]([H])([C@@H](O1)n1cnc3c1nc(N)[nH]c3=O)[C@@H]2O)n1cnc2c(N)ncnc12
InChI Key InChIKey=XRILCFTWUCUKJR-INFSMZHSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50506263
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of anti 6His antibody-labeled terbium cryptate binding to human wild-type full-length 6His-tagged d2-labeled STING measured after 4 hrs by...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [140-379](Homo sapiens (Human))
Shanghai Jemincare Pharmaceuticals
US Patent
Shanghai Jemincare Pharmaceuticals
US Patent
Affinity DataIC50: 6.66E+3nMAssay Description:Fluorescence polarization assay (FP assay) was used to detect the affinity of compounds for human STING proteins. There were a certain amount of fluo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair