BDBM4296 (2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Tyrphostin deriv. 29
SMILES Oc1ccc(\C=C(/C#N)C(=O)c2ccccc2)cc1O
InChI Key InChIKey=QBKFKKGORMOFFU-MDWZMJQESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4296
Affinity DataIC50: 1.30E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Tennessee Health Sciences Center
Curated by ChEMBL
University of Tennessee Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair