BDBM50250606 CHEMBL4077342

SMILES OP(O)(=O)C(F)(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=WGLNSQXDSIOHHO-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50250606   Sort by

TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  110nMAssay Description:Inhibition of STEP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectrophot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectrop...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of LMW-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed