BDBM50439496 CHEMBL2418096::US9169182, J23

SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl

InChI Key InChIKey=MKTUZAYNCRKLDS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50439496   

TargetCell division protein FtsZ(Escherichia coli (strain K12))
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.60E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetCell division protein FtsZ(Escherichia coli (strain K12))
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 4.40E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetCell division protein FtsZ(Bacillus subtilis)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed