BDBM50439496 CHEMBL2418096::US9169182, J23

SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl

InChI Key InChIKey=MKTUZAYNCRKLDS-YIXHJXPBSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50439496   

TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Bacillus subtilis)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.60E+4nMpH: 6.5 T: 2°CAssay Description:The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  4.40E+4nMpH: 6.5 T: 2°CAssay Description:The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...More data for this Ligand-Target Pair
In DepthDetails US Patent