BDBM50623175 CHEMBL5424844
SMILES COc1ccc2sc(cc2c1)C(=O)NNc1cc(Cl)cc(Cl)c1
InChI Key InChIKey=ZDJFIKFQLKJRBA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50623175
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CLK1 using GRSRSRSRSRSRSRS as substrate incubated for 15 mins in presence of ATP by gamma32P-ATP based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 13nMAssay Description:Inhibition of CLK4 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 51nMAssay Description:Binding affinity to NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells assessed as target engagement by measuring inhibition constant i...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 143nMAssay Description:Inhibition of human CLK2 using GRSRSRSRSRSRSRS as substrate incubated for 15 mins in presence of ATP by gamma32P-ATP based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 191nMAssay Description:Inhibition of DYRK1A (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 250nMAssay Description:Binding affinity to NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells assessed as target engagement incubated for 3 hrs by tracer K5 b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells incubated for 3 hrs in presence of ATP by tracer K5 based NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
