BDBM682152 8-(6-((2-(5-azaspiro[2.4]heptan-5-yl)ethoxy)methyl)pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]cinnolin-2(3H)-one::US20240207263, Example 102::US20240207263, Example 94
SMILES C[C@@H](OCCN1CCC2(CC2)C1)c1ccc2nnc3n(C)c(=O)n(C4CCOCC4)c3c2c1
InChI Key InChIKey=VDLCZWDWKCLEGK-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 682152
Affinity DataIC50: 5.5nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Suzhou Zanrong Pharma
US Patent
Suzhou Zanrong Pharma
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:PI3K Biochemical PotencyPI3Kα (p110α/p85a), PIK3C δ, PIK3Cβ (p110β), PIK3Cγ (pp110γ) kinase reaction solutions of ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Suzhou Zanrong Pharma
US Patent
Suzhou Zanrong Pharma
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:PI3K Biochemical PotencyPI3Kα (p110α/p85a), PIK3C δ, PIK3Cβ (p110β), PIK3Cγ (pp110γ) kinase reaction solutions of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:DNA-PK Biochemical AssayDNA-PK kinase reaction solutions of DNA-PK enzymes (Promega, Cat. No. V4106, Lot. No. 0000224016) were prepared in 1× kinase ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:mTOR Biochemical PotencySolution of mTOR enzymes (Millipore, Cat. No. 14-770) was prepared in 1× kinase buffer at 4-fold of the final concentration (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:ATR enzyme (batch: Eurofins Cat. No. 14-953) solutions were prepared in 1x kinase base buffer. 10 ul of 2x enzyme solution (final concentration: 2.5 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Suzhou Zanrong Pharma
US Patent
Suzhou Zanrong Pharma
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:PI3K Biochemical PotencyPI3Kα (p110α/p85a), PIK3C δ, PIK3Cβ (p110β), PIK3Cγ (pp110γ) kinase reaction solutions of ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Zanrong Pharma
US Patent
Suzhou Zanrong Pharma
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:PI3K Biochemical PotencyPI3Kα (p110α/p85a), PIK3C δ, PIK3Cβ (p110β), PIK3Cγ (pp110γ) kinase reaction solutions of ...More data for this Ligand-Target Pair