BDBM732804 3-[5-chloro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihydro-1H-isoquinoline-2- carbonyl]phenyl]-N-(4-hydroxyphenyl)-N- [(3-methoxy-2-methyl-phenyl)methyl]- 5,6,7,8-tetrahydroindolizine-1-carboxamide::US20250115577, Compound 4

SMILES COc1cccc(CN(C(=O)c2cc(-c3cc(Cl)ccc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n3c2CCCC3)c2ccc(O)cc2)c1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 732804   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732804(3-[5-chloro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihy...)
Affinity DataIC50: 5nMAssay Description:BPS Bioscience, #50222: 3 ng of BCL-2, 5 μL of 1:100 anti-His Tb-labeled donor, 5 μL of 1:100 Dye-labeled acceptor, 5 L of 1:40 BCL-2 Peptide Ligand,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetApoptosis regulator Bcl-2 [G101V](Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732804(3-[5-chloro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihy...)
Affinity DataIC50: 550nMAssay Description:0.22 ng/μl of BCL-2 (SinoBiological, #10195-H08E1), 5 μL of 1:100 anti-His Tb-labeled donor, 5 μL of 1:100 Dye-labeled acceptor, 5 μL of 1:40 BCL-2 P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732804(3-[5-chloro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihy...)
Affinity DataIC50: 5.00E+3nMAssay Description:BPS Bioscience, #50223: 10.5 ng of BCL-xL, 5 μL of 1:120 anti-His Tb-labeled donor, 5 μL of 1:120 Dye-labeled acceptor, 5 μL of 1:96 BCL-xL Peptide L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent