BDBM84684 1-Subsituted 1H-imidazole, 21::CHEMBL543494

SMILES OC(=O)CCCCn1ccnc1

InChI Key InChIKey=YTRRZWTXQVETAL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 84684   

TargetCytochrome P450 2A6(Human)
University of Basel

LigandPNGBDBM84684(1-Subsituted 1H-imidazole, 21 | CHEMBL543494)
Affinity DataIC50:  1.78E+5nMpH: 7.6 T: 37°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2A13(Human)
University of Basel

LigandPNGBDBM84684(1-Subsituted 1H-imidazole, 21 | CHEMBL543494)
Affinity DataIC50:  8.20E+4nMpH: 7.6 T: 37°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM84684(1-Subsituted 1H-imidazole, 21 | CHEMBL543494)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Thromboxane synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM84684(1-Subsituted 1H-imidazole, 21 | CHEMBL543494)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM84684(1-Subsituted 1H-imidazole, 21 | CHEMBL543494)
Affinity DataIC50:  2.24E+5nMAssay Description:Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM84684(1-Subsituted 1H-imidazole, 21 | CHEMBL543494)
Affinity DataIC50:  1.15E+5nMAssay Description:Inhibition of mouse GAT1-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed