BDBM50022775 (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate::3-Trimethylammoniumphenyl N,N-dimethylcarbamate::3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium::CHEMBL211471::CHEMBL278020::Eustigmin::Eustigmine::NEOSTIGMINE::Neostigmine (2)::Prostigmine::Vagostigmine::m-Trimethylammoniumphenyldimethylcarbamate
SMILES CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
InChI Key InChIKey=ALWKGYPQUAPLQC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 60 hits for monomerid = 50022775
Affinity DataKi: 1.00E+3nMAssay Description:Tested for in vitro inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition assay using AChE and BuChE.More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition assay using AChE and BuChE.More data for this Ligand-Target Pair
Affinity DataIC50: 4.32E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+4nMAssay Description:Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+4nMAssay Description:Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMpH: 8.0 T: 2°CAssay Description:Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:In vitro inhibitory activity against acetylcholinesterase from electric eelMore data for this Ligand-Target Pair
Affinity DataIC50: 4.91E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of AChE (unknown origin) using ACh chloride as substrate preincubated for 15 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of electric eel AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 42.1nMAssay Description:Inhibition of human serum AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 37.5nMAssay Description:Inhibition of rat brain homogenate AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Wistar rat brain homogenate AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human serum AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of guinea pig acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human serum AChE by Ellman colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47.5nMAssay Description:Inhibition of electric eel AChE by Ellman colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Wistar rat brain AChE by Ellman colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of equine serum BChE using butylthiocholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 91.0nMAssay Description:Inhibition acetylcholinesterase (AChE) enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 18.8nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of equine BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of AChE in rat brain cortexMore data for this Ligand-Target Pair