BDBM10887 Sulfamate 7::Topiramate (TPM)::US11535599, Example topiramate::[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
SMILES CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
InChI Key InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 10887
Affinity DataKi: 9nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human carbonic anhydrase 5B after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of human carbonic anhydrase 9 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair