BDBM10887 Sulfamate 7::Topiramate (TPM)::US11535599, Example topiramate::[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
SMILES CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
InChI Key InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 67 hits for monomerid = 10887
Affinity DataKi: 0.870nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human carbonic anhydrase 7More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human recombinant CA7 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human recombinant full length CA7-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant human CA7 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human recombinant CA12 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human carbonic anhydrase 12More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Compound was evaluated for inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ki value against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ki value against human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of recombinant human CA2 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant full length carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant full length CA2-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant CA2 cytosolic isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human carbonic anhydrase 5BMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human recombinant CA5B by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human recombinant CA5B mitochondrial isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of human carbonic anhydrase 6More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of human recombinant CA6 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of mouse carbonic anhydrase 13More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of human recombinant CA13 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Compound was evaluated for inhibition against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibitory activity against carbonic anhydrase isolated from bovine lung microsome (bCA IV)More data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Compound was evaluated for inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of human carbonic anhydrase-9 catalytic domain assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped flow a...More data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of full length human CA9 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 catalytic domain by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of human recombinant CA9 catalytic domain-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of human carbonic anhydrase 5AMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of human recombinant CA5A by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of human recombinant CA5A mitochondrial isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Inhibition of mouse recombinant CA15 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human recombinant CA1 cytosolic isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Compound was evaluated for inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibitory activity against human carbonic anhydrase I (hCAI)More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Ki value against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair