BDBM10888 1,2-benzoxazol-3-ylmethanesulfonamide::CHEMBL750::SPR_2::US10172837, Zonisamide::Zonisamide::Zonisamide (ZNA)::Zonisamide (ZNS)::Zonisamide, 1::Zonisamide, ZNS

SMILES NS(=O)(=O)Cc1noc2ccccc12

InChI Key InChIKey=UBQNRHZMVUUOMG-UHFFFAOYSA-N

Data  143 KI  2 IC50  3 Kd  1 Koff  1 Kon

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10888   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kirklareli University

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Affinity DataKi:  41nM ΔG°:  -10.1kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kirklareli University

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Affinity DataKi:  60nM ΔG°:  -9.85kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarbonic anhydrase 6(Homo sapiens (Human))
Kirklareli University

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Affinity DataKi:  95nM ΔG°:  -9.57kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed