BDBM119763 US8685958, 12

SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CC(C1)Oc1ccc(CN2CCCC22COC2)cc1

InChI Key InChIKey=PGYVQEAAPZQCSN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 119763   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM119763(US8685958, 12)
Affinity DataIC50:  45nMAssay Description:Melanin Concentrating Hormone Receptor 1 (MCHR1) is a G-protein coupled receptor that interacts with heterotrimeric G proteins containing a Gαi/...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM119763(US8685958, 12)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM119763(US8685958, 12)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM119763(US8685958, 12)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed