BDBM15364 4-chloro-6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol::CCT018159 analog 3
SMILES Cc1[nH]nc(c1-c1ccc2OCCOc2c1)-c1cc(Cl)c(O)cc1O
InChI Key InChIKey=RTIAXUYLACAMGU-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 15364
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
TargetVirulence sensor histidine kinase PhoQ(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of recombinant Salmonella typhimurium N-terminal His6-SUMO-tagged DHp-catalytic domain PhoQ (257 to 487 residues) autophosphorylation expr...More data for this Ligand-Target Pair