BDBM15365 3-(2,4-Dihydroxyphenyl)-4-(4-methoxyphenyl)-5-methyl-1H-pyrazole::4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol::CCT018159 analog 4

SMILES COc1ccc(cc1)-c1c(C)[nH]nc1-c1ccc(O)cc1O

InChI Key InChIKey=GSBFARPNIZUMHA-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15365   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM15365(3-(2,4-Dihydroxyphenyl)-4-(4-methoxyphenyl)-5-meth...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHistidine kinase(Caulobacter vibrioides)
Williams College

Curated by ChEMBL
LigandPNGBDBM15365(3-(2,4-Dihydroxyphenyl)-4-(4-methoxyphenyl)-5-meth...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM15365(3-(2,4-Dihydroxyphenyl)-4-(4-methoxyphenyl)-5-meth...)
Affinity DataIC50:  6.48E+5nMAssay Description:Inhibition of PDHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed