BDBM16998 Indolinone based compound, 7g::[(3Z)-3-{[4-(3-methoxyphenyl)-1H-pyrrol-2-yl]methylidene}-2-oxo-2,3-dihydro-1H-indol-5-yl]urea

SMILES COc1cccc(c1)-c1c[nH]c(\C=C2/C(=O)Nc3ccc(NC(N)=O)cc23)c1

InChI Key InChIKey=RULBQJYTXYLQOK-ZDLGFXPLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16998   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM16998(Indolinone based compound, 7g | [(3Z)-3-{[4-(3-met...)
Affinity DataIC50:  19nMpH: 7.2 T: 2°CAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed