BDBM191903 US9187429, 36::US9187429, 37::US9187429, 38

SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc(Cl)c(F)c1

InChI Key InChIKey=BTXHAHICPWSTRI-UHFFFAOYSA-N

Data  1 IC50  6 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 191903   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  1.01E+3nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  3.14E+4nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  214nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  1.26E+3nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  7nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataEC50:  14nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair