BDBM19266 CHEMBL410745::Mycophenolic Adenine Dinucleotide (MAD) Analogue, 37::[({[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl][2-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)ethoxy]phosphinic acid
SMILES COc1c(C)c2COC(=O)c2c(O)c1CCOP(O)(=O)CP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccccc1
InChI Key InChIKey=NQFZDJMITHLHES-VUZJQGPZSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 19266
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University of Minnesota At Twin Citiies
University of Minnesota At Twin Citiies
Affinity DataKi: 66nM ΔG°: -9.79kcal/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University of Minnesota At Twin Citiies
University of Minnesota At Twin Citiies
Affinity DataKi: 70nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota At Twin Citiies
University of Minnesota At Twin Citiies
Affinity DataKi: 108nM ΔG°: -9.50kcal/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota At Twin Citiies
University of Minnesota At Twin Citiies
Affinity DataKi: 110nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair