BDBM193852 (E)-3-(2-(2-(1-(4-bromophenyl)ethylidene)hydrazinyl)thiazol-4-yl)-2H-chromen-2-one (6e)

SMILES C\C(=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)c1ccc(Br)cc1

InChI Key InChIKey=CMZRBLFQISWUPQ-FSJBWODESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 193852   

TargetAldo-keto reductase family 1 member A1(Bos taurus (Cattle))
Comsats Institute of Information Technology

LigandPNGBDBM193852((E)-3-(2-(2-(1-(4-bromophenyl)ethylidene)hydraziny...)
Affinity DataIC50:  1.71E+3nMpH: 6.2Assay Description:The assay results were obtained at 340 nm and ALR1 inhibitory activity was measured with the absorbance change at this respective wavelength. Each we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193852((E)-3-(2-(2-(1-(4-bromophenyl)ethylidene)hydraziny...)
Affinity DataIC50:  110nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology

LigandPNGBDBM193852((E)-3-(2-(2-(1-(4-bromophenyl)ethylidene)hydraziny...)
Affinity DataIC50:  110nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed