BDBM209921 Norbinaltorphimine (nor-BNI)

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O

InChI Key InChIKey=APSUXPSYBJVPPS-YHMFJAFCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209921   

TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM209921(Norbinaltorphimine (nor-BNI))
Affinity DataIC50:  2.10nMAssay Description:β-Arrestin2 translocation was also studied using the PathHunter® β-arrestin assay in CHO-K1 cells expressing the KOR (DiscoveRx, Fremont, C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM209921(Norbinaltorphimine (nor-BNI))
Affinity DataIC50:  0.460nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed