Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM209921'
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM209921(Norbinaltorphimine (nor-BNI))
Affinity DataIC50:  0.460nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM209921(Norbinaltorphimine (nor-BNI))
Affinity DataIC50:  2.10nMAssay Description:β-Arrestin2 translocation was also studied using the PathHunter® β-arrestin assay in CHO-K1 cells expressing the KOR (DiscoveRx, Fremont, C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed