BDBM209923 5'-Guanidinonaltrindole (5'-GNTI)

SMILES NC(N)=Nc1ccc2[nH]c3[C@@H]4Oc5c6c(C[C@@H]7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c2c1)ccc5O

InChI Key InChIKey=VLNHDKDBGWXJEE-HZVPBQBQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209923   

TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM209923(5'-Guanidinonaltrindole (5'-GNTI))
Affinity DataIC50:  0.800nMAssay Description:β-Arrestin2 translocation was also studied using the PathHunter® β-arrestin assay in CHO-K1 cells expressing the KOR (DiscoveRx, Fremont, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM209923(5'-Guanidinonaltrindole (5'-GNTI))
Affinity DataIC50:  0.0700nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed