BDBM21613 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid::N-(3 ,4 -dimethoxycinnamoyl)anthranilic acid::Rizaben::Tranilast

SMILES COc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1OC

InChI Key InChIKey=NZHGWWWHIYHZNX-CSKARUKUSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21613   

TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Roche Innovation Center Shanghai

Curated by ChEMBL

LigandBDBM21613(2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benz...)Copy SMILESCopy InChI

Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed C57BL/6 mouse bone marrow derived macrophages incubated for 30 mins in presence of ATP by i...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI