BDBM217366 Pep2-8::TVFTSWEEYLDWV
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C(C)C)C(N)=O
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 217366
Affinity DataIC50: 1.40E+3nMAssay Description:For the peptide affinity determinations, biotinylated PCSK9 was immobilized to NeutrAvidin-coated MaxiSorp Immuno-Plates and incubated with a mixture...More data for this Ligand-Target Pair
Affinity DataKd: 700nMAssay Description:Binding affinity to recombinant human C-terminal His8-tagged PCSK9 expressed in Chinese hamster ovary cells by biolayer interferometryMore data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Inhibition of PCSK9 in human HepG2 cells assessed as increase in LDL uptakeMore data for this Ligand-Target Pair
Affinity DataKd: 700nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of PCSK9 in human HepG2 cells assessed as restoration of LDLRMore data for this Ligand-Target Pair
Affinity DataKd: 9.70E+3nMAssay Description:Binding affinity to human PCSK9 by surface plasmon resonanceMore data for this Ligand-Target Pair