BDBM218202 US9249087, 43

SMILES ONC(=O)c1ccc(Cn2cccn2)cc1

InChI Key InChIKey=DUGDSZFLAKVUEC-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 218202   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  1.47E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  10.9nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  46nMAssay Description:Inhibition of HDAC6 in mouse N2A cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataEC50:  932nMAssay Description:Inhibition of HDAC6 in mouse N2A cells assessed as increase in alpha tubulin acetylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  6.86E+3nMAssay Description:Inhibition of HDAC1 in mouse N2A cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed