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Found 5 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM218202'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  10.9nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Mus musculus)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  46nMAssay Description:Inhibition of HDAC6 in mouse N2A cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataEC50:  932nMAssay Description:Inhibition of HDAC6 in mouse N2A cells assessed as increase in alpha tubulin acetylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed