BDBM221073 SPHINX scaffold, 3::US9695160, SPHINX7::US9796707, Reference Compound SPHINX7
SMILES CN(C)CCN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(o1)-c1ccncc1)C(F)(F)F
InChI Key InChIKey=ALLIMXLDTJFWHR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 221073
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 7.45 T: 2°CAssay Description:Whole cell patch clamp recordings of hERG current (IhERG) were made at 37 °C from human embryonic kidney cells (HEK 293) cells stably expressing ...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of SRPK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 54.7nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 55nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair