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Found 4 Enz. Inhib. hit(s) with Target = 'SRSF protein kinase 1' and Ligand = 'BDBM221073'
TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM221073(SPHINX scaffold, 3 | US9695160, SPHINX7 | US979670...)
Affinity DataIC50:  54.7nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM221073(SPHINX scaffold, 3 | US9695160, SPHINX7 | US979670...)
Affinity DataIC50:  55nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM221073(SPHINX scaffold, 3 | US9695160, SPHINX7 | US979670...)
Affinity DataIC50:  59nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM221073(SPHINX scaffold, 3 | US9695160, SPHINX7 | US979670...)
Affinity DataIC50:  59nMAssay Description:Inhibition of SRPK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed