BDBM223489 US9320734, 360
SMILES CC1=NN(C(=O)c2ccc(O)cc2)C(=O)C1\N=N\c1ccc(cc1)S(=O)(=O)Nc1ncccn1
InChI Key InChIKey=LOTBGJBJYRKOGT-OCOZRVBESA-N
Data 6 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 223489
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.30E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 2.40E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 420nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.35E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.74E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.07E+4nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair