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Found 2 Enz. Inhib. hit(s) with Target = 'Insulin receptor substrate 1 [1-264]' and Ligand = 'BDBM223489'
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM223489(US9320734, 360)
Affinity DataKd:  1.74E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM223489(US9320734, 360)
Affinity DataKd:  1.07E+4nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent