BDBM225320 CS246

SMILES CC(=O)N=S([O-])(=O)c1ccc(N\C=C2/C(=O)Nc3ccc4ncsc4c23)cc1

InChI Key InChIKey=IVMUZUPWYGYMJU-JYRVWZFOSA-M

Data  2 Kd  2 Koff  2 Kon  2 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 225320   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225320(CS246)
Affinity DataKd:  207nMAssay Description:OctetRed_Method2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225320(CS246)
Affinity DataKoff:  1.08E+5s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225320(CS246)
Affinity DataKon:  0.0592M-1s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225320(CS246)
Affinity DataKd:  526nMAssay Description:OctetRed_Method1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225320(CS246)
Affinity DataKoff:  1.14E+5s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225320(CS246)
Affinity DataKon:  0.0160M-1s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 225320   

CellCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

SyringePNGBDBM225320(CS246)
ITC DataΔG°: -9.12kcal/mole −TΔS°: -1.86kcal/mole ΔH°: -7.24kcal/mole logk: 4.97E+6
T: 24.85°C 
Syringe InfoPC cidPC sid
In DepthDetails PubMed
CellCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

SyringePNGBDBM225320(CS246)
ITC DataΔG°: -9.15kcal/mole −TΔS°: 5.81kcal/mole ΔH°: -15.0kcal/mole logk: 5.17E+6
T: 24.85°C 
Syringe InfoPC cidPC sid
In DepthDetails PubMed