BDBM22880 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine::4-Methylhistamine::Methylhistamine-4

SMILES Cc1nc[nH]c1CCN

InChI Key InChIKey=UGYXPZQILZRKJJ-UHFFFAOYSA-N

Data  5 KI  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 22880   

TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at mouse histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2 by steady-state GTPase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human histamine H2 receptor expressed in Sf9 cells coexpressing Gsalphas by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at rat histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Met...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed