BDBM24567 (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate::CHEMBL175247::Orlistat::THLP::Tetrahydrolipstatin::US9328123, Orlistat::Xenical

SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O

InChI Key InChIKey=AHLBNYSZXLDEJQ-FWEHEUNISA-N

Data  5 KI  59 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 24567   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant FAAH transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylserine lipase ABHD16A(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant ABHD12 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant KIAA1363 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant PLA2g7 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant DAGLalpha overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed