BDBM24964 organophosphorus derivative, 5::{[(2S)-2-amino-3-phenylpropanamido]methyl}(methyl)phosphinic acid

SMILES CP(O)(=O)CNC(=O)[C@@H](N)Cc1ccccc1

InChI Key InChIKey=VSYRLEOKFZDZRX-JTQLQIEISA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24964   

TargetUrease subunit alpha [F36L]/beta/gamma(Proteus vulgaris)
Wroclaw University of Technology

LigandPNGBDBM24964(organophosphorus derivative, 5 | {[(2S)-2-amino-3-...)
Affinity DataKi:  1.76E+5nM ΔG°:  -5.20kcal/mole IC50:  7.54E+5nMpH: 7.0 T: 2°CAssay Description:Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease subunit alpha/beta/gamma(Bacillus pasteurii)
Wroclaw University of Technology

LigandPNGBDBM24964(organophosphorus derivative, 5 | {[(2S)-2-amino-3-...)
Affinity DataKi:  2.15E+5nM ΔG°:  -5.08kcal/mole IC50:  6.00E+5nMpH: 7.0 T: 2°CAssay Description:Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed