BDBM26292 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6-methoxyquinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215275::pyrazoloquinazoline deriv., 26
SMILES CCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)c2cc1OC
InChI Key InChIKey=HOHHMYNNRAVKQB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 26292
Affinity DataIC50: 270nMAssay Description:Inhibition of aurora B in human SW620 cells assessed as inhibition of histone H3 phosphorylationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of aurora B kinaseChecked by AuthorMore data for this Ligand-Target Pair