BDBM26976 2-benzoylquinazoline analogue, (1R, 2S)-17::N-(4-{[(1S,2R)-2-carbamimidamidocyclohexyl]amino}-6-methylquinazolin-2-yl)-4-chlorobenzamide

SMILES [#6]-c1ccc2nc(-[#7]-[#6](=O)-c3ccc(Cl)cc3)nc(-[#7]-[#6@H]-3-[#6]-[#6]-[#6]-[#6]-[#6@H]-3\[#7]=[#6](/[#7])-[#7])c2c1

InChI Key InChIKey=QMDMBZRAKLLSDM-RBUKOAKNSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26976   

TargetNociceptin receptor(Homo sapiens (Human))
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  1.40nM ΔG°:  -12.1kcal/molepH: 7.8 T: 2°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  330nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  510nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed