BDBM308131 US9649309, Compound UNC2876A
SMILES CCCCNc1ncc(C(=O)NC2CCN(CC3CC3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1
InChI Key InChIKey=IVQYTNHIHIIOCN-KESTWPANSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 308131
TargetGrowth arrest-specific protein 6(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 150nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 49nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 3.60nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 218nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 49nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary el...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 3.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 150nMAssay Description:Inhibition of Tyro3 (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Affinity DataIC50: 218nMAssay Description:Inhibition of Axl (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary ele...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: <10nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair