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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM308131'
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  3.60nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50: <10nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent