BDBM313604 5-chloro-N-(3-(6- ethoxy-5-(tetrahydro- 2H-pyran-4-yl) pyridazin-3-yl)-4- methylphenyl)-4- (trifluoromethyl) picolinamide::US10167279, Example 228

SMILES CCOc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2cc(c(Cl)cn2)C(F)(F)F)ccc1C

InChI Key InChIKey=UORSDJKSEPMQEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313604   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM313604(5-chloro-N-(3-(6- ethoxy-5-(tetrahydro- 2H-pyran-4...)
Affinity DataIC50:  60nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent