BDBM32147 AS-229::CHLOROXINE::cid_2722

SMILES Oc1c(Cl)cc(Cl)c2cccnc12

InChI Key InChIKey=WDFKMLRRRCGAKS-UHFFFAOYSA-N

Data  14 IC50  2 Kd  4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32147   

TargetReplicase polyprotein 1ab(2019-nCoV)
The State University Of New Jersey

Curated by ChEMBL

LigandBDBM32147(AS-229 | CHLOROXINE | cid_2722)Copy SMILESCopy InChI

Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to biotin-tagged SARS-CoV-2 papain-like protease expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant incubate...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseChEBI
DrugBankMCE
PC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-14(Homo sapiens (Human))TBA

LigandBDBM32147(AS-229 | CHLOROXINE | cid_2722)Copy SMILESCopy InChI

Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to CMS sensor chip immobilized MMP-14 catalytic domain (unknown origin) assessed as equilibrium dissociation constant by surface pla...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
DrugBankMCE
PC cidPC sidPatentsSimilars

In DepthDetails PubMed
Copy BDB DOI