BDBM32289 2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3-dione::2-[(1-prop-2-ynylindol-3-yl)methylidene]indene-1,3-dione::2-[(1-propargylindol-3-yl)methylene]indane-1,3-quinone::2-{[1-(2-propyn-1-yl)-1H-indol-3-yl]methylene}-1H-indene-1,3(2H)-dione::MLS000574697::SMR000196125::cid_807202

SMILES O=[#6]-1\[#6](=[#6]\c2cn(-[#6]C#C)c3ccccc23)-[#6](=O)-c2ccccc-12

InChI Key InChIKey=CPMAYZAGQGWDSZ-UHFFFAOYSA-N

Data  5 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 32289   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataEC50:  1.17E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataEC50:  9.57E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataIC50:  5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataEC50:  9.02E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataEC50:  1.38E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataEC50:  1.63E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataIC50:  6.36E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32289(2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3...)
Affinity DataEC50:  1.78E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay